Symbol
Name
ID

Msi2
musashi RNA-binding protein 2
MGI:1923876

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

small thymus

thymus hypoplasia

decreased DN2 thymocyte number

decreased DN3 thymocyte number

decreased common myeloid progenitor cell number

decreased immature B cell number

decreased double-negative T cell number

decreased double-positive T cell number

abnormal bone marrow cell morphology/development

decreased bone marrow cell number

abnormal common lymphocyte progenitor cell morphology

decreased erythrocyte cell number

decreased neutrophil cell number

decreased granulocyte number

increased mean platelet volume

decreased mature B cell number

decreased B cell number

decreased pre-B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased lymphocyte cell number

decreased macrophage cell number

decreased leukocyte cell number

decreased hematopoietic stem cell number

abnormal myeloid leukocyte morphology

abnormal spleen morphology

decreased spleen weight

small spleen

spleen hypoplasia

abnormal hematopoietic stem cell physiology

Availability

Mouse Genotype

Msi2^em1(IMPC)Mbp/Msi2^em1(IMPC)Mbp

Msi2^{Gt(Ayu21-T2)Imeg}/Msi2^{Gt(Ayu21-T2)Imeg}

Msi2^{Gt(E035H03)Wrst}/Msi2^{Gt(E035H03)Wrst}

Msi2^tm1.1Cjl/Msi2^tm1.1Cjl
Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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